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TOMM20

Description translocase of outer mitochondrial membrane 20
Image
GO Annotations Cellular Component
  • Mitochondrion
  • Mitochondrial Outer Membrane
  • Mitochondrial Outer Membrane Translocase Complex
  • Integral Component Of Mitochondrial Outer Membrane
  • Mitochondria-associated Endoplasmic Reticulum Membrane
Molecular Function
  • Protein Binding
  • Protein Transmembrane Transporter Activity
  • P-P-bond-hydrolysis-driven Protein Transmembrane Transporter Activity
  • Mitochondrion Targeting Sequence Binding
  • Unfolded Protein Binding
Biological Process
  • Protein Targeting To Mitochondrion
  • Response To Muscle Activity
  • TRNA Import Into Mitochondrion
  • Macroautophagy
  • Protein Deubiquitination
  • Protein Import Into Mitochondrial Matrix
  • Response To 3,3',5-triiodo-L-thyronine
Pathways
  • Mitochondrial protein import
  • PINK1-PRKN Mediated Mitophagy
  • Ub-specific processing proteases
Drugs
Diseases
GWAS
  • Apolipoprotein A1 levels ( 32203549)
  • Cholesterol, total ( 20686565)
  • Cobalt levels ( 26025379)
  • Immune reponse to smallpox (secreted IL-2) ( 22610502)
  • LDL cholesterol ( 20686565)
  • LDL cholesterol levels ( 32203549)
  • Night sleep phenotypes ( 27126917)
  • Obesity-related traits ( 23251661)
Interacting Genes 19 interacting genes: AIP APOA1 ATXN1 BAG6 BCL2 CDC73 CEP126 DHFR FBXO7 FEZ1 HAP1 HSD17B10 OTC PPHLN1 PTN TOMM22 TOMM40 UCP1 VDAC1
Entrez ID 9804
HPRD ID 03507
Ensembl ID ENSG00000173726
Uniprot IDs A0A024R3W2 Q15388
PDB IDs 4APO
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025