CABLES1

Description		Cdk5 and Abl enzyme substrate 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol
	Molecular Function	Protein Binding
	Biological Process	Cell Cycle Cell Division Regulation Of Cell Cycle
Pathways		Cyclin E associated events during G1/S transition Cyclin A:Cdk2-associated events at S phase entry Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Birth weight ( 31043758) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) FEV1 ( 30804560) Heel bone mineral density ( 30598549) Height ( 28552196 20881960 25282103 25429064 23563607 31562340 28270201 18391951 20189936) High density lipoprotein cholesterol levels ( 31928498) Hip circumference adjusted for BMI ( 28552196 25673412) Hypertriglyceridemia ( 23505323) Initial pursuit acceleration ( 29064472) Initial pursuit acceleration in psychotic disorders ( 29064472) Lung adenocarcinoma ( 28604730) Lung function (FVC) ( 30061609 30804560) Mean platelet volume ( 32888494 27863252) Monocyte count ( 27863252) Neurofibrillary tangles ( 31497858) Platelet count ( 22139419 24026423 29403010 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Scalp hair shape ( 26926045) Sitting height ratio ( 25865494) Smoking behavior ( 19247474) Tuberculosis ( 20694014) Waist circumference ( 31928498) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for BMI in smokers ( 28443625) Waist circumference adjusted for body mass index ( 28552196 25673412 28448500) White blood cell count ( 32888494)
Novel Interacting Genes		1 novel interacting genes: MIB1
Interacting Genes		8 interacting genes: ABL1 CCNA1 CCNE1 CDK3 CDK5 TDRD7 TP53 TP73
Entrez ID		91768
HPRD ID		16461
Ensembl ID		ENSG00000134508
Uniprot IDs		A0A024RC20 A7K6Y5 Q8TDN4
PDB IDs
Enriched GO Terms of Interacting Partners?
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