RPS6KA4

Description		ribosomal protein S6 kinase A4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Ribosomal Protein S6 Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Negative Regulation Of Cytokine Production Regulation Of Transcription, DNA-templated Protein Phosphorylation Inflammatory Response Histone Phosphorylation Peptidyl-serine Phosphorylation Positive Regulation Of CREB Transcription Factor Activity Positive Regulation Of Histone Phosphorylation Positive Regulation Of Histone Acetylation Intracellular Signal Transduction Histone H3-S10 Phosphorylation Histone H3-S28 Phosphorylation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of NF-kappaB Transcription Factor Activity Interleukin-1-mediated Signaling Pathway
Pathways		Recycling pathway of L1
Drugs		Flavin mononucleotide
Diseases
GWAS		Crohn's disease ( 28067908) Inflammatory bowel disease ( 23128233) Leprosy ( 22019778) Offspring birth weight ( 31043758) Primary biliary cholangitis ( 21399635) Primary biliary cirrhosis ( 22961000) Psoriasis ( 23143594) Serum uric acid levels ( 32514006)
Novel Interacting Genes		1 novel interacting genes: PDE2A
Interacting Genes		9 interacting genes: ATF1 CREB1 FOS HMGN1 MAP2K1 MAPK1 MAPK14 MAPK3 NEDD4
Entrez ID		8986
HPRD ID		04677
Ensembl ID		ENSG00000162302
Uniprot IDs		A0PJF8 B4DPV1 E9PJN1 O75676
PDB IDs
Enriched GO Terms of Interacting Partners?
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