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ALDH1A2
Description
aldehyde dehydrogenase 1 family member A2
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Perinuclear Region Of Cytoplasm
Molecular Function
Retinal Dehydrogenase Activity
3-chloroallyl Aldehyde Dehydrogenase Activity
Aldehyde Dehydrogenase (NAD+) Activity
Retinal Binding
Biological Process
Blood Vessel Development
Kidney Development
Liver Development
Regulation Of Endothelial Cell Proliferation
Retinoic Acid Biosynthetic Process
Heart Morphogenesis
Vitamin A Metabolic Process
Midgut Development
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Determination Of Bilateral Symmetry
Proximal/distal Pattern Formation
Positive Regulation Of Gene Expression
Neural Crest Cell Development
Morphogenesis Of Embryonic Epithelium
Neural Tube Development
Pituitary Gland Development
Neuron Differentiation
Lung Development
Hindbrain Development
Pancreas Development
Embryonic Camera-type Eye Development
Response To Estradiol
Response To Vitamin A
Response To Cytokine
Embryonic Forelimb Morphogenesis
Ureter Maturation
Retinol Metabolic Process
Retinoic Acid Metabolic Process
Retinal Metabolic Process
9-cis-retinoic Acid Biosynthetic Process
Positive Regulation Of Apoptotic Process
Embryonic Digestive Tract Development
Cardiac Muscle Tissue Development
Protein Homotetramerization
Face Development
Cellular Response To Retinoic Acid
Retinoic Acid Receptor Signaling Pathway Involved In Somitogenesis
Pathways
RA biosynthesis pathway
Drugs
NADH
Vitamin A
Tretinoin
Diseases
GWAS
Barrett's esophagus (
27527254
)
Barrett's esophagus or Esophageal adenocarcinoma (
27527254
)
Brain morphology (MOSTest) (
32665545
)
Cholesterol (
31902109
)
Diisocyanate-induced asthma (
25918132
)
Eosinophil counts (
32888494
)
HDL cholesterol (
28270201
30275531
)
HDL cholesterol levels x short total sleep time interaction (2df test) (
31719535
)
Height (
28552196
)
Hematocrit (
32888494
)
Hemoglobin (
32888494
)
Hypertension (
19609347
)
Ischemic stroke (
26089329
)
LDL cholesterol (
30275531
)
Low density lipoprotein cholesterol levels (
32154731
)
Low HDL-cholesterol levels (
31910446
)
Lymphocyte counts (
32888494
)
Medication use (HMG CoA reductase inhibitors) (
31015401
)
Monocyte count (
32888494
)
Osteoarthritis (hand, severe) (
24728293
)
Red blood cell count (
32888494
)
Small cell lung carcinoma (
28604730
)
Stroke (
26089329
)
Total cholesterol levels (
30275531
)
Triglyceride levels (
32154731
)
Uncontrolled blood pressure in combination therapy (beta blocker and thiazide diuretic) (
29097388
)
Interacting Genes
1 interacting genes:
HTRA2
Entrez ID
8854
HPRD ID
04733
Ensembl ID
ENSG00000128918
Uniprot IDs
O94788
PDB IDs
4X2Q
6ALJ
6B5G
6B5H
6B5I
Enriched GO Terms of Interacting Partners
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