DNAH11

Description		dynein axonemal heavy chain 11
Image		No pdb structure
GO Annotations	Cellular Component	Microtubule Axoneme Dynein Complex Motile Cilium 9+2 Motile Cilium Proximal Portion Of Axoneme
	Molecular Function	ATP Binding ATP-dependent Microtubule Motor Activity, Minus-end-directed Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding
	Biological Process	Cilium Movement Regulation Of Cilium Beat Frequency Microtubule-based Movement Determination Of Left/right Symmetry Flagellated Sperm Motility
Pathways
Drugs
Diseases		Primary ciliary dyskinesia, including: Primary ciliary dyskinesia; Kartagener syndrome
GWAS		Apolipoprotein B levels ( 32203549) Bipolar disorder ( 31043756) Bone mineral density (hip) ( 30172743) Brain morphology (MOSTest) ( 32665545) Breast cancer ( 29059683) Cholesterol, total ( 24097068 19060911 25961943 20686565) Cognitive decline (age-related) ( 24468470) Gut microbiota relative abundance (unclassified genus belonging to family Clostridiaceae) ( 33208821) LDL cholesterol ( 24097068 19060911 30275531 25961943 20686565) LDL cholesterol levels ( 32203549 28334899) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Low density lipoprotein cholesterol levels ( 32154731) Medication use (drugs for peptic ulcer and gastro-oesophageal reflux disease) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401) Metabolite levels ( 23823483) Metabolite levels (lipoprotein measures) ( 27005778) Multiple cancers (lung cancer, gastric cancer, and squamous cell carcinoma) ( 23103227) Multiple myeloma ( 22120009 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) PR interval ( 32439900) Serum omega-6 polyunsaturated fatty acid concentration in metabolic syndrome ( 31991592) Serum total polyunsaturated fatty acid concentration in metabolic syndrome ( 31991592) Subcortical volume (MOSTest) ( 32665545) Total cholesterol levels ( 28334899 30275531) Total ventricular volume ( 21116278) Whole-brain volume ( 21116278)
Novel Interacting Genes		3 novel interacting genes: CPVL GGCT IL6
Interacting Genes
Entrez ID		8701
HPRD ID		09134
Ensembl ID		ENSG00000105877
Uniprot IDs		H9NAJ7 H9NAJ8 Q96DT5 Q96NT7
PDB IDs
Enriched GO Terms of Interacting Partners?
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