PDXK

Description		pyridoxal kinase
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GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytosol Secretory Granule Lumen Specific Granule Lumen Extracellular Exosome
	Molecular Function	Magnesium Ion Binding ATP Binding Zinc Ion Binding Pyridoxal Kinase Activity Pyridoxal Phosphate Binding Potassium Ion Binding Sodium Ion Binding Lithium Ion Binding Protein Homodimerization Activity
	Biological Process	Pyridoxal 5'-phosphate Salvage Phosphorylation Vitamin B6 Metabolic Process Neutrophil Degranulation
Pathways		Neutrophil degranulation Vitamins B6 activation to pyridoxal phosphate
Drugs		Pyridoxal Pyridoxine Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate O6-(R)-ROSCOVITINE, R-2-(6-BENZYLOXY-9-ISOPROPYL-9H-PURIN-2-YLAMINO)-BUTAN-1-OL (2R)-2-({6-[benzyl(methyl)amino]-9-isopropyl-9H-purin-2-yl}amino)butan-1-ol
Diseases
GWAS		Blood protein levels ( 30072576) Refractive error ( 32231278) Systolic blood pressure change trajectories ( 27980656)
Novel Interacting Genes		2 novel interacting genes: GET1 RIPK1
Interacting Genes		2 interacting genes: BARD1 YWHAQ
Entrez ID		8566
HPRD ID		01526
Ensembl ID		ENSG00000160209
Uniprot IDs		F2Z2Y4 O00764 V9HWC3
PDB IDs		2AJP 2F7K 2YXT 2YXU 3FHX 3FHY 3KEU 4EN4 4EOH
Enriched GO Terms of Interacting Partners?
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