RNF135

Description		ring finger protein 135
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoplasmic Stress Granule Ribonucleoprotein Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding RIG-I Binding Identical Protein Binding Ribonucleoprotein Complex Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Free Ubiquitin Chain Polymerization Protein Ubiquitination Negative Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production RIG-I Signaling Pathway Innate Immune Response Regulation Of Innate Immune Response Protein Homooligomerization Protein K63-linked Ubiquitination Antiviral Innate Immune Response
Pathways		DDX58/IFIH1-mediated induction of interferon-alpha/beta Ovarian tumor domain proteases TRAF3-dependent IRF activation pathway TRAF6 mediated IRF7 activation TRAF6 mediated NF-kB activation TRAF6 mediated NF-kB activation NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 Negative regulators of DDX58/IFIH1 signaling Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Height ( 18391951)
Interacting Genes		9 interacting genes: CTBP2 CTNNAL1 DDX58 ENOX2 GOLGA2 HSF2BP TEPSIN UBE2D2 UBE2N
Entrez ID		84282
HPRD ID		11506
Ensembl ID		ENSG00000181481
Uniprot IDs		B3KV69 Q8IUD6
PDB IDs
Enriched GO Terms of Interacting Partners?
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