ADAMTS10

Description		ADAM metallopeptidase with thrombospondin type 1 motif 10
Image		No pdb structure
GO Annotations	Cellular Component	Microfibril Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Molecular_function Metalloendopeptidase Activity Protein Binding Metal Ion Binding
	Biological Process	Proteolysis Biological_process Extracellular Matrix Organization
Pathways		Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
Drugs
Diseases		Weill-Marchesani syndrome, including: Weill-Marchesani syndrome; Weill-Marchesani-like syndrome
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Appendicular lean mass ( 33097823) Asthma ( 30929738) Asthma (childhood onset) ( 30929738) Atopic dermatitis ( 26482879) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body size at age 10 ( 32376654) Carpal tunnel syndrome ( 30833571) Height ( 28552196 20881960 25282103 18391951) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Resting metabolic rate ( 28476931) Tonsillectomy ( 27182965 28928442) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412)
Interacting Genes		7 interacting genes: ANXA7 CDKN1A HMGCL LAMTOR3 PCYT2 SMN1 TK1
Entrez ID		81794
HPRD ID		07470
Ensembl ID		ENSG00000142303
Uniprot IDs		A0A0A0MQW6 Q59FE5 Q6ZN14 Q9H324
PDB IDs
Enriched GO Terms of Interacting Partners?
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