ADAMTS12

Description		ADAM metallopeptidase with thrombospondin type 1 motif 12
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Matrix
	Molecular Function	Metalloendopeptidase Activity Protein Binding Metal Ion Binding
	Biological Process	Cell-matrix Adhesion Cell Migration Proteoglycan Catabolic Process Extracellular Matrix Organization Negative Regulation Of Chondrocyte Differentiation Regulation Of Inflammatory Response Proteolysis Involved In Cellular Protein Catabolic Process Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Cellular Response To BMP Stimulus Regulation Of Endothelial Tube Morphogenesis Negative Regulation Of Hepatocyte Growth Factor Receptor Signaling Pathway Negative Regulation Of Cellular Response To Vascular Endothelial Growth Factor Stimulus Negative Regulation Of Cellular Response To Hepatocyte Growth Factor Stimulus
Pathways		Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Height ( 31217584) Metabolite levels ( 23823483) Mortality in heart failure ( 20400778) Neurofibrillary tangles ( 31497858) Seasonality and depression ( 30217971) Stroke (pediatric) ( 22990015)
Interacting Genes		7 interacting genes: CALM2 COIL IHO1 MEOX2 MYL6 TP53BP2 TRIM14
Entrez ID		81792
HPRD ID		05862
Ensembl ID		ENSG00000151388
Uniprot IDs		D6REX0 P58397
PDB IDs
Enriched GO Terms of Interacting Partners?
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