NHEJ1

Description		non-homologous end joining factor 1
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GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm DNA Ligase IV Complex Nonhomologous End Joining Complex
	Molecular Function	Protein Binding DNA End Binding
	Biological Process	Double-strand Break Repair Via Nonhomologous End Joining Central Nervous System Development Response To Ionizing Radiation B Cell Differentiation T Cell Differentiation Positive Regulation Of Ligase Activity
Pathways		Nonhomologous End-Joining (NHEJ)
Drugs
Diseases		Severe combined immunodeficiency with microcephaly, growth retardation, and sensitivity to ionizing radiation; NHEJ1 syndrome
GWAS		Height ( 25282103 25429064 31562340) Serum polyunsaturated fatty acid concentration x sex interaction in metabolic syndrome ( 31991592) Thyroid stimulating hormone levels ( 32769997)
Interacting Genes		2 interacting genes: LIG4 XRCC4
Entrez ID		79840
HPRD ID		07784
Ensembl ID		ENSG00000187736
Uniprot IDs		Q9H9Q4
PDB IDs		2QM4 2R9A 3Q4F 3RWR 3SR2 3W03 6ERG 6ERH
Enriched GO Terms of Interacting Partners?
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