GSDMD

Description		gasdermin D
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleoplasm Cytosol Plasma Membrane Integral Component Of Membrane Specific Granule Lumen NLRP3 Inflammasome Complex Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Phosphatidylserine Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidic Acid Binding Cardiolipin Binding
	Biological Process	Inflammatory Response Positive Regulation Of Interleukin-1 Beta Production Pore Formation In Membrane Of Other Organism Defense Response To Bacterium Neutrophil Degranulation Innate Immune Response Pore Complex Assembly Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Protein Homooligomerization Pyroptosis
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Schizophrenia ( 31268507)
Interacting Genes		8 interacting genes: ASPG KCTD6 MEOX2 MFHAS1 PSMA1 ZBTB33 ZNF426 ZNF558
Entrez ID		79792
HPRD ID		11014
Ensembl ID		ENSG00000104518
Uniprot IDs		P57764
PDB IDs		5NH1 5WQT 6AO4 6KN0 6N9O
Enriched GO Terms of Interacting Partners?
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