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PALB2

Description partner and localizer of BRCA2
Image
GO Annotations Cellular Component
  • Nucleoplasm
Molecular Function
  • DNA Binding
  • Protein Binding
Biological Process
  • Double-strand Break Repair Via Homologous Recombination
  • Somitogenesis
  • Inner Cell Mass Cell Proliferation
  • Mesoderm Development
  • Animal Organ Morphogenesis
  • Multicellular Organism Growth
  • Post-anal Tail Morphogenesis
  • Negative Regulation Of Apoptotic Process
  • Embryonic Organ Development
Pathways
  • HDR through Homologous Recombination (HRR)
  • Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
  • Resolution of D-loop Structures through Holliday Junction Intermediates
  • Homologous DNA Pairing and Strand Exchange
Drugs
Diseases
  • Fanconi anemia
GWAS
  • Bipolar disorder ( 17554300)
Interacting Genes 32 interacting genes: BCAS3 BRCA2 CASZ1 CCL5 CST6 DIRAS3 ERRFI1 GREB1 H2BC3 H3C1 H4C1 HNRNPC IL13RA2 IL24 KEAP1 KLK6 LRATD2 LYPD3 MRC2 NAT2 PDS5B PRDM14 RAD51 RAD51AP1 RAD51C RHOBTB2 RNF168 SERPINB5 SNAI1 THRSP USP2 XRCC3
Entrez ID 79728
HPRD ID 07966
Ensembl ID ENSG00000083093
Uniprot IDs H3BN63 Q86YC2
PDB IDs 2W18 3EU7
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025