VRK1

Description		VRK serine/threonine kinase 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Stack Spindle Cytosol
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Kinase Binding Nucleosomal Histone Binding Histone Kinase Activity (H3-S10 Specific) Histone Kinase Activity (H3-T3 Specific) Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Protein Phosphorylation Mitotic Nuclear Envelope Disassembly Mitotic Nuclear Envelope Reassembly Peptidyl-serine Phosphorylation Histone H3-S10 Phosphorylation Protein Autophosphorylation Cell Division Histone H3-T3 Phosphorylation Golgi Disassembly
Pathways		Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation
Drugs
Diseases		Pontocerebellar hypoplasia
GWAS		Bone ultrasound measurement (velocity of sound) ( 28472463) Carboplatin disposition in epthelial ovarian cancer ( 29367611) Cognitive function ( 24684796) Copper levels ( 26025379) Fractures (paediatric) ( 32742401) Metabolite levels ( 23823483) Neutrophil count ( 21507922) Night sleep phenotypes ( 27126917) Staphylococcus aureus infection ( 24847357)
Interacting Genes		6 interacting genes: H2BC21 H3C14 NBN PLK3 SRPK2 TP53
Entrez ID		7443
HPRD ID		03701
Ensembl ID		ENSG00000100749
Uniprot IDs		Q99986
PDB IDs		2KTY 2KUL 2LAV 2RSV 3OP5 5UKF 5UVF 6AC9 6BP0 6BRU 6BTW 6BU6 6CFM 6CMM 6CNX 6CQH 6CSW 6DD4 6NPN 6VZH
Enriched GO Terms of Interacting Partners?
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