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SRY
Description
sex determining region Y
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Speck
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA Binding
Calmodulin Binding
Transcription Factor Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription, DNA-templated
Sex Differentiation
Anatomical Structure Morphogenesis
Positive Regulation Of Gene Expression
Cell Differentiation
Male Sex Determination
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Male Gonad Development
Pathways
Deactivation of the beta-catenin transactivating complex
Transcriptional regulation of testis differentiation
Drugs
Diseases
46,XX disorders of sex development (Disorders of gonadal development), including: Ovotesticular DSD; Testicular DSD; Ovarian dysgenesis
46,XY disorders of sex development (Disorders of gonadal development), including: Gonadal agenesis; Complete and partial gonadal dysgenesis; Testis regression; Ovotesticular DSD
GWAS
Novel Interacting Genes
1 novel interacting genes:
KAT8
Interacting Genes
7 interacting genes:
AR
EP300
HDAC3
KPNB1
SLC9A3R2
SMAD3
ZNF208
Entrez ID
6736
HPRD ID
08364
Ensembl ID
ENSG00000184895
Uniprot IDs
A7WPU8
Q05066
PDB IDs
1HRY
1HRZ
1J46
1J47
2GZK
6EDB
Enriched GO Terms of Interacting Partners
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Tagcloud
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