SPTB

Description		spectrin beta, erythrocytic
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GO Annotations	Cellular Component	Cytosol Spectrin Spectrin-associated Cytoskeleton Actin Cytoskeleton Intrinsic Component Of The Cytoplasmic Side Of The Plasma Membrane Protein-containing Complex
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Ankyrin Binding Actin Filament Binding
	Biological Process	MAPK Cascade Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cytoskeleton Organization Axon Guidance Actin Filament Capping
Pathways		NCAM signaling for neurite out-growth NCAM signaling for neurite out-growth Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins RAF/MAP kinase cascade COPI-mediated anterograde transport
Drugs
Diseases		Hereditary elliptocytosis (HE) Hereditary spherocytosis (SPH)
GWAS		Daytime sleep phenotypes ( 27126917) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Lymphocyte counts ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Obesity-related traits ( 23251661) Pediatric areal bone mineral density (radius) ( 28181694) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Type 2 diabetes ( 31049640)
Novel Interacting Genes		1 novel interacting genes: RBPJ
Interacting Genes		17 interacting genes: ACTB ADD1 ANK1 AP1G1 CSRP3 DMTN ENO3 EPB41 MAPT NCAM1 SH2D2A SNAPIN SPTA1 SPTAN1 STAT1 TULP3 YWHAQ
Entrez ID		6710
HPRD ID		01686
Ensembl ID		ENSG00000070182
Uniprot IDs		P11277
PDB IDs		1S35 3EDU 3F57 3KBT 3KBU 3LBX
Enriched GO Terms of Interacting Partners?
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