SLC12A2

Description		solute carrier family 12 member 2
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GO Annotations	Cellular Component	Cytosol Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Membrane Apical Plasma Membrane Lateral Plasma Membrane Cytoplasmic Vesicle Membrane Cell Projection Membrane Cell Projection Neuron Projection Neuronal Cell Body Cell Body Cell Body Membrane Extracellular Exosome Cell Periphery Spanning Component Of Membrane Extracellular Vesicle
	Molecular Function	Protein Binding Sodium:potassium:chloride Symporter Activity Ammonium Transmembrane Transporter Activity Potassium Ion Transmembrane Transporter Activity Cation:chloride Symporter Activity Potassium:chloride Symporter Activity Protein Kinase Binding Metal Ion Transmembrane Transporter Activity Chaperone Binding Hsp90 Protein Binding
	Biological Process	Ion Transport Cellular Sodium Ion Homeostasis Cell Volume Homeostasis Hyperosmotic Response Gamma-aminobutyric Acid Signaling Pathway Aging T Cell Chemotaxis Ammonium Transport Cellular Potassium Ion Homeostasis Transepithelial Chloride Transport Cellular Chloride Ion Homeostasis Maintenance Of Blood-brain Barrier Sodium Ion Transmembrane Transport Cellular Response To Potassium Ion Positive Regulation Of Cell Volume Chloride Ion Homeostasis Potassium Ion Homeostasis Sodium Ion Homeostasis Negative Regulation Of Vascular Wound Healing Transepithelial Ammonium Transport Ammonium Transmembrane Transport Inorganic Anion Import Across Plasma Membrane Inorganic Cation Import Across Plasma Membrane Sodium Ion Import Across Plasma Membrane Regulation Of Spontaneous Synaptic Transmission Transport Across Blood-brain Barrier Chloride Transmembrane Transport Positive Regulation Of Aspartate Secretion Regulation Of Matrix Metallopeptidase Secretion Potassium Ion Import Across Plasma Membrane Cellular Response To Chemokine
Pathways		Cation-coupled Chloride cotransporters
Drugs		Torasemide Potassium chloride Bumetanide Quinethazone
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Beard thickness ( 26926045) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction) ( 19023125) HDL cholesterol levels ( 32203549) Height ( 25282103 31562340) Ileal carcinoids ( 21139019) Immature fraction of reticulocytes ( 32888494) Pelvic organ prolapse ( 32184442) Red cell distribution width ( 28957414) Statin-induced myopathy ( 31220337)
Interacting Genes		3 interacting genes: COMMD1 OXSR1 STK39
Entrez ID		6558
HPRD ID		06775
Ensembl ID		ENSG00000064651
Uniprot IDs		B7ZM24 P55011 Q53ZR1
PDB IDs		6PZT
Enriched GO Terms of Interacting Partners?
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