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COP1

Description COP1 E3 ubiquitin ligase
Image
GO Annotations Cellular Component
  • Golgi Membrane
  • Nucleoplasm
  • Cytosol
  • Nuclear Speck
  • Cul4A-RING E3 Ubiquitin Ligase Complex
Molecular Function
  • Ubiquitin-protein Transferase Activity
  • Protein Binding
  • Metal Ion Binding
  • Ubiquitin Protein Ligase Activity
Biological Process
  • Response To Ionizing Radiation
  • Protein Ubiquitination
  • Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
  • Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
  • Post-translational Protein Modification
Pathways
  • Autodegradation of the E3 ubiquitin ligase COP1
  • Neddylation
Drugs
Diseases
GWAS
Interacting Genes 19 interacting genes: CCT4 CDKN1B DET1 ETS1 ETS2 JUN JUND MLF1 PTPN1 RB1CC1 SFN SIPA1 SOX2 STK40 TP53 TRIB1 UBE2D1 UBE2D2 YWHAZ
Entrez ID 64326
HPRD ID 07455
Ensembl ID ENSG00000143207
Uniprot IDs Q8NHY2 X5D7N8 X5DNY7
PDB IDs 5HQG 5IGQ
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2023