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SDHA
Description
succinate dehydrogenase complex flavoprotein subunit A
Image
GO Annotations
Cellular Component
Nucleolus
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Respiratory Chain Complex II, Succinate Dehydrogenase Complex (ubiquinone)
Molecular Function
Succinate Dehydrogenase Activity
Protein Binding
Succinate Dehydrogenase (ubiquinone) Activity
Electron Transfer Activity
Flavin Adenine Dinucleotide Binding
Biological Process
Tricarboxylic Acid Cycle
Succinate Metabolic Process
Mitochondrial Electron Transport, Succinate To Ubiquinone
Nervous System Development
Respiratory Electron Transport Chain
Pathways
Respiratory electron transport
Citric acid cycle (TCA cycle)
Drugs
2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
Carboxin
Thenoyltrifluoroacetone
Ubiquinone Q1
Ubidecarenone
Diseases
Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
Diseases of the tricarboxylic acid cycle, including: Fumarase (FH) deficiency; Succinate dehydrogenase (SDH) deficiency; Alpha-ketoglutarate dehydrogenase (AKGDH) deficiency
GWAS
Interacting Genes
5 interacting genes:
CDC42
CSNK2B
ERCC6
HSPB2
WBP2
Entrez ID
6389
HPRD ID
02914
Ensembl ID
ENSG00000073578
Uniprot IDs
A0A024QZ30
D6RFM5
P31040
PDB IDs
6VAX
Enriched GO Terms of Interacting Partners
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