SCN3A

Description		sodium voltage-gated channel alpha subunit 3
Image		No pdb structure
GO Annotations	Cellular Component	Voltage-gated Sodium Channel Complex Cytoplasm Axon
	Molecular Function	Voltage-gated Ion Channel Activity Voltage-gated Sodium Channel Activity
	Biological Process	Sodium Ion Transport Neuronal Action Potential Regulation Of Ion Transmembrane Transport Sodium Ion Transmembrane Transport Membrane Depolarization During Action Potential
Pathways		Interaction between L1 and Ankyrins Phase 0 - rapid depolarisation
Drugs		Ranolazine Phenytoin Topiramate Valproic acid Lamotrigine Carbamazepine Oxcarbazepine Cocaine Zonisamide Promethazine Tetrodotoxin Brivaracetam Lacosamide Tetracaine Amylocaine Propoxycaine Pramocaine Pentoxyverine Dichlorobenzyl alcohol Bioallethrin Fish oil
Diseases
GWAS		Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Epilepsy ( 30531953) Focal epilepsy ( 30531953) Generalized epilepsy ( 30531953) Metabolite levels ( 23823483) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Parkinson's disease ( 28892059) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Novel Interacting Genes		1 novel interacting genes: GET1
Interacting Genes		5 interacting genes: CNTN1 LRP1 LRP2 LRP8 PRKCG
Entrez ID		6328
HPRD ID		01671
Ensembl ID		ENSG00000153253
Uniprot IDs		A0A590UJH3 Q9C007 Q9NY46
PDB IDs
Enriched GO Terms of Interacting Partners?
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