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SARS1

Description seryl-tRNA synthetase 1
Image
GO Annotations Cellular Component
  • Nucleus
  • Cytoplasm
  • Cytosol
  • Extracellular Exosome
Molecular Function
  • TRNA Binding
  • RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
  • RNA Binding
  • Serine-tRNA Ligase Activity
  • Protein Binding
  • ATP Binding
  • Enzyme Binding
  • Protein Homodimerization Activity
Biological Process
  • Negative Regulation Of Transcription By RNA Polymerase II
  • Translation
  • TRNA Aminoacylation For Protein Translation
  • Seryl-tRNA Aminoacylation
  • TRNA Processing
  • Selenocysteine Metabolic Process
  • Negative Regulation Of Angiogenesis
  • Selenocysteinyl-tRNA(Sec) Biosynthetic Process
  • Negative Regulation Of Vascular Endothelial Growth Factor Production
Pathways
  • Selenocysteine synthesis
  • Cytosolic tRNA aminoacylation
Drugs
  • Serine
Diseases
GWAS
Novel Interacting Genes 1 novel interacting genes: PTPN22
Interacting Genes 6 interacting genes: LINC01554 POT1 SUMO2 TERF1 TINF2 TRS-AGA2-3
Entrez ID 6301
HPRD ID 09605
Ensembl ID ENSG00000031698
Uniprot IDs P49591 Q0VGA5 Q5T5C7
PDB IDs 3VBB 4L87 4RQE 4RQF
Enriched GO Terms of Interacting Partners?
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