PAPPA2

Description		pappalysin 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Apical Plasma Membrane Extracellular Exosome
	Molecular Function	Metallopeptidase Activity Zinc Ion Binding
	Biological Process	Regulation Of Cell Growth Proteolysis Response To Salt Stress Cellular Protein Metabolic Process Bone Morphogenesis
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Automobile speeding propensity ( 30643258) Birth weight ( 31043758) Body mass index ( 26426971) Fractional exhaled nitric oxide (childhood) ( 24315451) GIP levels in response to oral glucose tolerance test (120 minutes) ( 29093273) Height ( 20881960 25429064 31562340) Offspring birth weight ( 31043758) Perioperative myocardial infarction in coronary artery bypass surgery ( 25948407) Pulse pressure ( 27841878 30578418) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in inactive individuals ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes		5 interacting genes: ATF7IP IGFBP3 IGFBP5 SMAD4 ZNF512B
Entrez ID		60676
HPRD ID		10156
Ensembl ID		ENSG00000116183
Uniprot IDs		Q9BXP8
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?