RASGRF2

Description		Ras protein specific guanine nucleotide releasing factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Calmodulin Binding
	Biological Process	MAPK Cascade G Protein-coupled Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Response To Endoplasmic Reticulum Stress Regulation Of Rho Protein Signal Transduction Positive Regulation Of Apoptotic Process Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction Long-term Synaptic Potentiation Regulation Of NMDA Receptor Activity
Pathways		NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events Ras activation upon Ca2+ influx through NMDA receptor RAF/MAP kinase cascade
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Eating disorders ( 23568457) Eating disorders (purging via substances) ( 23568457) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549 28869591) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Mucinous adenocarcinoma in colorectal cancer ( 29942513) Orofacial clefts ( 22419666) Response to ketamine in bipolar disorder or major depression (dissociation effects) ( 30552317) Response to methylphenidate treatment in attention-deficit/hyperactivity disorder (blood pressure) ( 21130132) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Statin-induced myopathy (severe) ( 31220337) Superior frontal gyrus grey matter volume ( 25335168)
Interacting Genes		5 interacting genes: AKTIP CDC42 KRAS RAC1 RHOA
Entrez ID		5924
HPRD ID		07588
Ensembl ID		ENSG00000113319
Uniprot IDs		A0A2X0SFL3 O14827 Q68DX5
PDB IDs
Enriched GO Terms of Interacting Partners?
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