TNRC6C

Description		trinucleotide repeat containing adaptor 6C
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GO Annotations	Cellular Component	P-body Nucleoplasm Cytosol
	Molecular Function	RNA Binding Protein Binding
	Biological Process	Wnt Signaling Pathway, Calcium Modulating Pathway Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Post-transcriptional Gene Silencing By RNA Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Regulation Of Megakaryocyte Differentiation Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Pathways		Pre-NOTCH Transcription and Translation Oxidative Stress Induced Senescence Oncogene Induced Senescence Ca2+ pathway Post-transcriptional silencing by small RNAs TP53 Regulates Metabolic Genes MAPK6/MAPK4 signaling Transcriptional Regulation by VENTX Regulation of RUNX1 Expression and Activity RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Regulation of PTEN mRNA translation Competing endogenous RNAs (ceRNAs) regulate PTEN translation Transcriptional Regulation by MECP2 Transcriptional Regulation by MECP2 Estrogen-dependent gene expression Regulation of MECP2 expression and activity NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs
Diseases
GWAS		Normal facial asymmetry (angle of deformation score) ( 30631343) Refractive error ( 32231278) Serum uric acid levels ( 29559957) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Uterine fibroid number (single vs multiple) ( 30196971)
Novel Interacting Genes		1 novel interacting genes: RPTOR
Interacting Genes		2 interacting genes: AGO4 UBC
Entrez ID		57690
HPRD ID		10026
Ensembl ID		ENSG00000078687
Uniprot IDs		Q9HCJ0
PDB IDs		2DKL 2X04 3KTP
Enriched GO Terms of Interacting Partners?
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