PLEKHG5

Description		pleckstrin homology and RhoGEF domain containing G5
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Lamellipodium Endocytic Vesicle Axon Perinuclear Region Of Cytoplasm
	Molecular Function
	Biological Process	G Protein-coupled Receptor Signaling Pathway Rho Protein Signal Transduction Endothelial Cell Chemotaxis Positive Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Endothelial Cell Migration Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
Drugs
Diseases		Spinal muscular atrophy (SMA), including: SMA type I (SMA1) / Werdning-Hoffman disease; SMA type II (SMA2); SMA type III (SMA3) / Kugeleberg-Welander disease; SMA type IV (SMA4); X-linked SMA 2 (SMAX2); X-linked distal SMA 3 (DSMAX); Distal SMA autosomal recessive type 4 (DSMA4); Congenital distal spinal muscular atrophy (SMAL); SMA proximal adult autosomal dominant (SMAPAD)
GWAS		Multiple sclerosis ( 24076602) QT interval ( 19305408)
Interacting Genes		1 interacting genes: AHCYL1
Entrez ID		57449
HPRD ID		11104
Ensembl ID		ENSG00000171680
Uniprot IDs		O94827
PDB IDs
Enriched GO Terms of Interacting Partners?
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