HHAT

Description		hedgehog acyltransferase
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding GTP Binding O-acyltransferase Activity Palmitoyltransferase Activity Transferase Activity, Transferring Acyl Groups
	Biological Process	Smoothened Signaling Pathway Multicellular Organism Development Protein Palmitoylation
Pathways		Hedgehog ligand biogenesis HHAT G278V doesn't palmitoylate Hh-Np
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Ankylosing spondylitis ( 23749187) Body mass index (change over time) in chronic obstructive pulmonary disease ( 28044437) Body mass index (change over time) in lung cancer or chronic obstructive pulmonary disease ( 28044437) Cardiovascular disease in hypertension (ACE inhibitor interaction) ( 26516778) Heel bone mineral density ( 30598549 28869591) Intake of total sugars ( 31005972) Mosquito bite size ( 28199695) Neurofibrillary tangles ( 31497858) Post bronchodilator FEV1/FVC ratio in smoking ( 30068317) Post bronchodilator percent predicted FEV1 in smoking ( 30068317) Schizophrenia ( 23142968) Triglyceride levels ( 32203549)
Interacting Genes		1 interacting genes: SDCBP
Entrez ID		55733
HPRD ID		12041
Ensembl ID		ENSG00000054392
Uniprot IDs		B7Z2U8 B7Z5N1 Q5VTY9
PDB IDs		6P64 6UJO 6UJQ 6UK2 6UK4
Enriched GO Terms of Interacting Partners?
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