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MFN1

Description mitofusin 1
Image
GO Annotations Cellular Component
  • Mitochondrion
  • Mitochondrial Outer Membrane
  • Integral Component Of Membrane
  • Intrinsic Component Of Mitochondrial Outer Membrane
  • Integral Component Of Mitochondrial Outer Membrane
  • Outer Mitochondrial Membrane Protein Complex
Molecular Function
  • GTPase Activity
  • Protein Binding
  • GTP Binding
  • Identical Protein Binding
Biological Process
  • Mitochondrial Fusion
  • Positive Regulation Of Mitochondrial Membrane Potential
  • Macroautophagy
  • GTP Metabolic Process
  • Mitochondrion Localization
  • Mitochondrial Membrane Fusion
Pathways
  • PINK1-PRKN Mediated Mitophagy
  • Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
  • Gout (normal type) ( 32238385)
  • Plateletcrit ( 32888494)
  • Response to antidepressants (symptom improvement) ( 29160301)
Interacting Genes 2 interacting genes: BAK1 PRKN
Entrez ID 55669
HPRD ID 16344
Ensembl ID ENSG00000171109
Uniprot IDs Q8IWA4
PDB IDs 5GNR 5GNS 5GNT 5GNU 5GO4 5GOE 5GOF 5GOM 5YEW
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025