TMEM106B

Description		transmembrane protein 106B
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Integral Component Of Membrane Late Endosome Membrane
	Molecular Function	Molecular_function Protein Binding
	Biological Process	Lysosome Organization Lysosomal Transport Lysosome Localization Dendrite Morphogenesis
Pathways
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors) ( 23648065) Alzheimer's disease (APOE e4 interaction) ( 25778476) Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 30072576) Coronary artery disease ( 29212778 33020668) Crohn's disease ( 32581322) Depression ( 29700475) Differential aging (frontal cortex) ( 28330615) Differential aging in older adults (frontal cortex) ( 28330615) Experiencing mood swings ( 29500382) Frontotemporal dementia ( 29724592) Frontotemporal dementia with GRN mutation ( 29724592) General factor of neuroticism ( 30867560) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Idiopathic dilated cardiomyopathy ( 29495422) Lifetime anxiety disorder ( 31748690) Neurociticism ( 29500382) Neuroticism ( 29255261) Plasma kynurenine levels in major depressive disorder ( 29317604) Residual cognition ( 28441426) Response to amphetamines ( 22952603) Response to taxane treatment (placlitaxel) ( 23006423) Tourette syndrome ( 22889924) Triglycerides ( 30275531)
Novel Interacting Genes		1 novel interacting genes: PHF14
Interacting Genes		1 interacting genes: TMEM106C
Entrez ID		54664
HPRD ID		07745
Ensembl ID		ENSG00000106460
Uniprot IDs		A0A024R9Z1 Q9NUM4
PDB IDs
Enriched GO Terms of Interacting Partners?
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