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SOX18
Description
SRY-box transcription factor 18
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Transcription Regulator Complex
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Sequence-specific Double-stranded DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Angiogenesis
Vasculogenesis
In Utero Embryonic Development
Hair Follicle Development
Vasculature Development
Lymphangiogenesis
Heart Looping
Outflow Tract Morphogenesis
Regulation Of Transcription, DNA-templated
Anatomical Structure Morphogenesis
Hair Cycle Process
Cell Differentiation
Embryonic Heart Tube Development
Blood Vessel Endothelial Cell Migration
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Cell Maturation
Stem Cell Fate Specification
Endocardium Formation
Lymphatic Endothelial Cell Differentiation
Endocardial Cell Differentiation
Establishment Of Endothelial Barrier
Regulation Of Stem Cell Proliferation
Pathways
Drugs
Diseases
Lymphedemas, including: Lymphedema, hereditary I; Lymphedema-distichiasis syndrome (LD); Hypotrichosis-lymphedema-telangiectasia syndrome (HLTS)
GWAS
Cerebrospinal AB1-42 levels in normal cognition (
29274321
)
Refractive error (
32231278
)
Interacting Genes
5 interacting genes:
AURKA
GKAP1
HMGB1
MECP2
MEF2C
Entrez ID
54345
HPRD ID
07208
Ensembl ID
ENSG00000203883
Uniprot IDs
P35713
PDB IDs
Enriched GO Terms of Interacting Partners
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