PIK3C2A

Description		phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Trans-Golgi Network Cytosol Plasma Membrane Phosphatidylinositol 3-kinase Complex Membrane Clathrin-coated Vesicle Vesicle Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	ATP Binding 1-phosphatidylinositol-3-kinase Activity Clathrin Binding Phosphatidylinositol 3-kinase Activity 1-phosphatidylinositol-4-phosphate 3-kinase Activity Phosphatidylinositol Binding Phosphatidylinositol-4,5-bisphosphate 3-kinase Activity Phosphatidylinositol Kinase Activity Phosphatidylinositol-3,4-bisphosphate 5-kinase Activity
	Biological Process	Phosphatidylinositol Biosynthetic Process Exocytosis Endocytosis Epidermal Growth Factor Receptor Signaling Pathway Insulin Receptor Signaling Pathway Positive Regulation Of Autophagy Phosphatidylinositol 3-kinase Signaling Vascular Associated Smooth Muscle Contraction Cell Migration Phosphatidylinositol-3-phosphate Biosynthetic Process Phosphatidylinositol Phosphorylation Platelet-derived Growth Factor Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling Clathrin Coat Assembly Membrane Organization Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Pathways		Synthesis of PIPs at the plasma membrane Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the late endosome membrane Golgi Associated Vesicle Biogenesis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Body mass index ( 26426971) Platelet count ( 32888494) Schizophrenia or bipolar disorder ( 24280982) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes		3 interacting genes: AMOT EGFR ERBB2
Entrez ID		5286
HPRD ID		04672
Ensembl ID		ENSG00000011405
Uniprot IDs		B4DG55 L7RRS0 O00443
PDB IDs		2AR5 2IWL 2REA 2RED 6BTY 6BTZ 6BU0 6BUB
Enriched GO Terms of Interacting Partners?
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