PFKFB3

Description		6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Image
GO Annotations	Cellular Component	Nucleoplasm Cytosol
	Molecular Function	6-phosphofructo-2-kinase Activity Fructose-2,6-bisphosphate 2-phosphatase Activity Protein Binding ATP Binding
	Biological Process	Fructose Metabolic Process Fructose 2,6-bisphosphate Metabolic Process Dephosphorylation Positive Regulation Of Glycolytic Process Carbohydrate Phosphorylation
Pathways		Regulation of glycolysis by fructose 2,6-bisphosphate metabolism
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Asthma ( 31959851 31619474) Asthma (childhood onset) ( 31036433) Celiac disease ( 22057235 24999842) Crohn's disease ( 28067908) Latent autoimmune diabetes ( 30254083) Metabolite levels ( 23823483) Obesity (extreme) ( 31888951) Plasma anti-thyroid peroxidase levels ( 29678681) Response to chemotherapy in breast cancer hypertensive cases (cumulative dose) (bevacizumab) ( 25117820) Selective IgA deficiency ( 27723758) Western dietary pattern ( 28644415)
Novel Interacting Genes		2 novel interacting genes: GATA3 THAP1
Interacting Genes		2 interacting genes: GCK PFKFB1
Entrez ID		5209
HPRD ID		05612
Ensembl ID		ENSG00000170525
Uniprot IDs		B7Z8A0 Q16875
PDB IDs		2AXN 2DWO 2DWP 2I1V 3QPU 3QPV 3QPW 4D4J 4D4K 4D4L 4D4M 4MA4 5AJV 5AJW 5AJX 5AJY 5AJZ 5AK0 6ETJ 6HVH 6HVI 6HVJ 6IBX 6IBY 6IBZ 6IC0
Enriched GO Terms of Interacting Partners?
Tagcloud ?