PDE4C

Description		phosphodiesterase 4C
Image
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytosol Cilium Perinuclear Region Of Cytoplasm
	Molecular Function	3',5'-cyclic-nucleotide Phosphodiesterase Activity 3',5'-cyclic-AMP Phosphodiesterase Activity Metal Ion Binding
	Biological Process	CAMP Catabolic Process Signal Transduction G Protein-coupled Receptor Signaling Pathway
Pathways		DARPP-32 events G alpha (s) signalling events
Drugs		Caffeine Dyphylline Iloprost Amrinone Roflumilast Piclamilast Crisaborole Ibudilast Exisulind Trapidil
Diseases
GWAS		Apolipoprotein B levels ( 32203549) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731) Urate levels ( 31578528)
Novel Interacting Genes		1 novel interacting genes: GDF15
Interacting Genes		9 interacting genes: DDIT4L GSC2 KLRK1 MEOX1 MEOX2 OSGIN1 PAX6 SRI ZNF280A
Entrez ID		5143
HPRD ID		02529
Ensembl ID		ENSG00000105650
Uniprot IDs		O43849 P78505 Q08493 Q32MM7 Q7KYS4
PDB IDs		1LXU 2QYM
Enriched GO Terms of Interacting Partners?
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