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GMNN

Description geminin DNA replication inhibitor
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Cytosol
Molecular Function
  • Chromatin Binding
  • Transcription Corepressor Activity
  • Protein Binding
  • Histone Deacetylase Binding
  • Repressing Transcription Factor Binding
Biological Process
  • G1/S Transition Of Mitotic Cell Cycle
  • Regulation Of DNA Replication
  • Negative Regulation Of DNA Replication
  • Animal Organ Morphogenesis
  • Positive Regulation Of Chromatin Binding
  • Negative Regulation Of Cell Cycle
  • Negative Regulation Of Transcription, DNA-templated
  • DNA Replication Preinitiation Complex Assembly
  • Negative Regulation Of DNA-dependent DNA Replication
Pathways
  • CDT1 association with the CDC6:ORC:origin complex
  • Activation of the pre-replicative complex
Drugs
Diseases
GWAS
  • Metabolite levels ( 23823483)
Novel Interacting Genes 1 novel interacting genes: SHANK2
Interacting Genes 34 interacting genes: ARNT AURKA CASP3 CCDC146 CDKN1A CDKN2A CDT1 CSNK2A1 FZR1 GLIS2 HOXA10 HOXA11 HOXA7 HOXB7 HOXC8 HOXC9 HOXD10 IMPDH1 KANK2 KAT7 LNX1 MCM6 NCF1 PHC1 PTPN11 REPIN1 SAPCD2 SCMH1 SIX3 SMARCA4 UBE2C UBE2S ZNF250 ZNF439
Entrez ID 51053
HPRD ID 06783
Ensembl ID ENSG00000112312
Uniprot IDs A0A024QZY7 O75496
PDB IDs 1T6F 1UII 2LP0 2WVR 4BRY
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025