P2RY1

Description		purinergic receptor P2Y1
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GO Annotations	Cellular Component	Mitochondrion Plasma Membrane Integral Component Of Plasma Membrane Cilium Cell Surface Postsynaptic Density Basolateral Plasma Membrane Apical Plasma Membrane Dendrite Cell Body Postsynaptic Membrane Glutamatergic Synapse Integral Component Of Presynaptic Active Zone Membrane
	Molecular Function	G Protein-coupled ADP Receptor Activity Protein Binding ATP Binding A1 Adenosine Receptor Binding Signaling Receptor Activity ADP Binding G Protein-coupled Purinergic Nucleotide Receptor Activity G Protein-coupled ATP Receptor Activity Protein Heterodimerization Activity Scaffold Protein Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation G Protein-coupled Adenosine Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Aging Glial Cell Migration Regulation Of Cell Shape Response To Mechanical Stimulus Regulation Of Signaling Receptor Activity Negative Regulation Of Norepinephrine Secretion Sensory Perception Of Pain Signal Transduction Involved In Regulation Of Gene Expression Platelet Activation Positive Regulation Of Inositol Trisphosphate Biosynthetic Process G Protein-coupled Purinergic Nucleotide Receptor Signaling Pathway Eating Behavior Positive Regulation Of Ion Transport Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Hormone Secretion Negative Regulation Of Binding Positive Regulation Of Penile Erection Positive Regulation Of ERK1 And ERK2 Cascade Response To Growth Factor Cellular Response To ATP Cellular Response To Purine-containing Compound Protein Localization To Plasma Membrane Relaxation Of Muscle Blood Vessel Diameter Maintenance Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Synaptic Vesicle Exocytosis
Pathways		G alpha (q) signalling events P2Y receptors ADP signalling through P2Y purinoceptor 1 ADP signalling through P2Y purinoceptor 1
Drugs		Promethazine
Diseases
GWAS		Body mass index (change over time) in gastrointestinal cancer or chronic obstructive pulmonary disease ( 28044437) Chronotype ( 30696823) Immune reponse to smallpox (secreted IL-2) ( 22610502) Metabolite levels ( 23823483) Serum sulfate level ( 27412988)
Novel Interacting Genes		1 novel interacting genes: JAK1
Interacting Genes		3 interacting genes: ADORA1 SLC9A3R1 SLC9A3R2
Entrez ID		5028
HPRD ID		03103
Ensembl ID		ENSG00000169860
Uniprot IDs		P47900
PDB IDs		1Y36 4XNV 4XNW
Enriched GO Terms of Interacting Partners?
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