P2RX1

Description		purinergic receptor P2X 1
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Nuclear Inner Membrane Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Secretory Granule Membrane Protein-containing Complex Specific Granule Membrane Neuron Projection Membrane Raft Glutamatergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Active Zone Membrane
	Molecular Function	Purinergic Nucleotide Receptor Activity Extracellularly ATP-gated Cation Channel Activity Cation Channel Activity Protein Binding ATP Binding Drug Binding Zinc Ion Binding Identical Protein Binding Protein-containing Complex Binding
	Biological Process	Serotonin Secretion By Platelet Regulation Of Vascular Associated Smooth Muscle Contraction Ion Transport Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Signal Transduction Insemination Blood Coagulation Regulation Of Blood Pressure Neuronal Action Potential Platelet Activation Response To ATP Synaptic Transmission, Glutamatergic Purinergic Nucleotide Receptor Signaling Pathway Positive Regulation Of Ion Transport Neutrophil Degranulation Ceramide Biosynthetic Process Regulation Of Calcium Ion Transport Excitatory Postsynaptic Potential Cation Transmembrane Transport Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Synaptic Vesicle Exocytosis
Pathways		Elevation of cytosolic Ca2+ levels Platelet homeostasis Neutrophil degranulation
Drugs		Promethazine
Diseases
GWAS		Mean platelet volume ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Systemic sclerosis (anti-topoisomerase-positive) ( 29293537)
Interacting Genes		2 interacting genes: CYBC1 P2RX2
Entrez ID		5023
HPRD ID		07526
Ensembl ID		ENSG00000108405
Uniprot IDs		P51575
PDB IDs
Enriched GO Terms of Interacting Partners?
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