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MUC4

Description mucin 4, cell surface associated
Image No pdb structure
GO Annotations Cellular Component
  • Extracellular Space
  • Golgi Lumen
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • Membrane
  • Extracellular Matrix
  • Vesicle
  • Extracellular Exosome
Molecular Function
  • ErbB-2 Class Receptor Binding
  • Extracellular Matrix Constituent, Lubricant Activity
Biological Process
  • Stimulatory C-type Lectin Receptor Signaling Pathway
  • Cell-matrix Adhesion
  • Regulation Of Signaling Receptor Activity
  • O-glycan Processing
  • Maintenance Of Gastrointestinal Epithelium
Pathways
  • Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)
  • Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)
  • Defective GALNT12 causes colorectal cancer 1 (CRCS1)
  • Dectin-2 family
  • O-linked glycosylation of mucins
  • Termination of O-glycan biosynthesis
Drugs
Diseases
GWAS
  • Estimated glomerular filtration rate ( 31015462)
  • Lung disease severity in cystic fibrosis ( 26417704)
  • Red blood cell density in sickle cell anemia ( 28552477)
Interacting Genes 5 interacting genes: EGFR ERBB2 ERBB3 ERBB4 GALNT11
Entrez ID 4585
HPRD ID 11829
Ensembl ID ENSG00000145113
Uniprot IDs A0A0G2JS65 A0T3F4 E9PDY6 Q99102
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025