MT3

Description		metallothionein 3
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Synaptic Vesicle Inclusion Body Perinuclear Region Of Cytoplasm
	Molecular Function	Copper Ion Binding Protein Binding Zinc Ion Binding Antioxidant Activity Protein Kinase Activator Activity Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Cadmium Ion Binding Metal Ion Binding
	Biological Process	Response To Hypoxia Positive Regulation Of Protein Phosphorylation Energy Reserve Metabolic Process Cholesterol Catabolic Process Zinc Ion Transport Cellular Metal Ion Homeostasis Cellular Zinc Ion Homeostasis Apoptotic Process Response To Metal Ion Detoxification Of Copper Ion Negative Regulation Of Autophagy Positive Regulation Of Gene Expression Positive Regulation Of Necrotic Cell Death Positive Regulation Of Cell Death Negative Regulation Of Neuron Projection Development Astrocyte Development Histone Modification Removal Of Superoxide Radicals Negative Regulation Of Cell Growth Negative Regulation Of Axon Extension Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Response To Food Activation Of Protein Kinase B Activity Leptin-mediated Signaling Pathway Cellular Response To Oxidative Stress Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Negative Regulation Of Apoptotic Process Positive Regulation Of Catalytic Activity Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Protein Kinase B Signaling Negative Regulation Of Neuron Apoptotic Process Cellular Lipid Catabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Protein Stabilization Negative Regulation Of Oxidoreductase Activity Zinc Ion Homeostasis Cadmium Ion Homeostasis Regulation Of Protein Glycosylation Negative Regulation Of Necrotic Cell Death ERK1 And ERK2 Cascade Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Cadmium Ion Cellular Response To Copper Ion Cellular Response To Zinc Ion Cellular Response To Hypoxia Cellular Response To Nitric Oxide Positive Regulation Of Lysosomal Membrane Permeability Negative Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Oxygen Metabolic Process Negative Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Metallothioneins bind metals Metallothioneins bind metals
Drugs		Zinc Silver Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS
Interacting Genes		2 interacting genes: TERF2IP TTR
Entrez ID		4504
HPRD ID		00752
Ensembl ID		ENSG00000087250
Uniprot IDs		A0A024R6R7 P25713
PDB IDs		2F5H 2FJ4 2FJ5
Enriched GO Terms of Interacting Partners?
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