AFF3

Description		AF4/FMR2 family member 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Nuclear Body Super Elongation Complex
	Molecular Function	Double-stranded DNA Binding DNA-binding Transcription Factor Activity
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Response To Tumor Necrosis Factor Embryonic Hindlimb Morphogenesis
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first birth ( 27798627) Albumin-globulin ratio ( 29403010) Apolipoprotein A1 levels ( 32203549) Arthritis (juvenile idiopathic) ( 33106285) Autoimmune traits (pleiotropy) ( 30572963) Cannabis dependence symptom count ( 27028160) Celiac disease ( 30572963) Celiac disease and Rheumatoid arthritis ( 26546613) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Extremely high intelligence ( 29520040) Gastroesophageal reflux disease ( 31527586) General cognitive ability ( 29844566) Hand grip strength ( 29691431) HDL cholesterol levels ( 32203549) Height ( 31217584) Household income ( 27818178) Household income (MTAG) ( 31844048) IgG levels ( 28628107) Immature fraction of reticulocytes ( 32888494) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Intraocular pressure ( 29617998) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Kidney disease (end stage renal disease vs non-end stage renal disease) in type 1 diabetes ( 27647854) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Non-albumin protein levels ( 29403010) Number of children ever born ( 27798627) Plateletcrit ( 32888494 27863252) Red blood cell count ( 27863252) Refractive astigmatism ( 30306274) Regular attendance at a religious group ( 29970889) Rheumatoid arthritis ( 30423114 24782177 30572963 23143596 24390342 20453842) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) Serum total protein level ( 29403010) Type 1 diabetes ( 25751624 17554260) Type 1 diabetes nephropathy ( 23028342)
Novel Interacting Genes		5 novel interacting genes: DPP8 GPR137B IL18R1 IL18RAP ST6GAL2
Interacting Genes
Entrez ID		3899
HPRD ID		03272
Ensembl ID		ENSG00000144218
Uniprot IDs		P51826 Q8NAP7
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?