ISG20

Description		interferon stimulated exonuclease gene 20
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cajal Body PML Body
	Molecular Function	3'-5'-exoribonuclease Activity Exonuclease Activity Single-stranded DNA 3'-5' Exodeoxyribonuclease Activity Exoribonuclease II Activity U1 SnRNA Binding U2 SnRNA Binding U3 SnoRNA Binding Metal Ion Binding
	Biological Process	DNA Catabolic Process, Exonucleolytic RRNA Processing RNA Catabolic Process Response To Virus Negative Regulation Of Viral Genome Replication Defense Response To Virus Type I Interferon Signaling Pathway RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways		Interferon alpha/beta signaling
Drugs		Uridine monophosphate
Diseases
GWAS		Adult hearing aid use ( 31564434) Adult hearing difficulty ( 31564434) Age-related hearing impairment ( 27764096) Age-related hearing impairment (low/mid frequency) ( 31645637) Dupuytren's disease ( 28886342 21732829) Mean corpuscular hemoglobin ( 32888494) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Serum omega-6 polyunsaturated fatty acid concentration in metabolic syndrome ( 31991592) Serum total polyunsaturated fatty acid concentration in metabolic syndrome ( 31991592)
Novel Interacting Genes		2 novel interacting genes: NRG1 SCAND2P
Interacting Genes
Entrez ID		3669
HPRD ID		05169
Ensembl ID		ENSG00000172183
Uniprot IDs		Q96AZ6
PDB IDs		1WLJ
Enriched GO Terms of Interacting Partners?
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