HLA-F

Description		major histocompatibility complex, class I, F
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GO Annotations	Cellular Component	Golgi Membrane Extracellular Space Lysosomal Membrane Endoplasmic Reticulum Plasma Membrane External Side Of Plasma Membrane Cell Surface ER To Golgi Transport Vesicle Membrane Membrane Phagocytic Vesicle Membrane Early Endosome Membrane MHC Class Ib Protein Complex MHC Class I Protein Complex Recycling Endosome Membrane Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding Beta-2-microglobulin Binding Peptide Antigen Binding TAP1 Binding TAP2 Binding 14-3-3 Protein Binding
	Biological Process	Positive Regulation Of T Cell Mediated Cytotoxicity Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class Ib Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Negative Regulation Of T Cell Cytokine Production Negative Regulation Of Natural Killer Cell Cytokine Production Positive Regulation Of Natural Killer Cell Cytokine Production Immune Response Negative Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Degranulation Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway Negative Regulation Of Neuron Death
Pathways		ER-Phagosome pathway ER-Phagosome pathway Endosomal/Vacuolar pathway Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Interferon gamma signaling Interferon alpha/beta signaling Antigen Presentation: Folding, assembly and peptide loading of class I MHC Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 22412388) Mixed cellularity Hodgkin lymphoma ( 29196614) Nasopharyngeal carcinoma ( 19664746) Offspring birth weight ( 31043758)
Interacting Genes		5 interacting genes: B2M CHRM5 LILRB1 LILRB2 TAP1
Entrez ID		3134
HPRD ID		00884
Ensembl ID		ENSG00000204642
Uniprot IDs		P30511 Q5JZ47 Q5JZ48
PDB IDs		5IUE 5KNM
Enriched GO Terms of Interacting Partners?
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