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RGCC
Description
regulator of cell cycle
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Centrosome
Cytosol
Molecular Function
Protein Binding
Protein Kinase Binding
Protein Kinase Activator Activity
R-SMAD Binding
Biological Process
Negative Regulation Of Exit From Mitosis
Negative Regulation Of Cytokine Production
Positive Regulation Of Cytokine Production
Negative Regulation Of Endothelial Cell Proliferation
Positive Regulation Of Extracellular Matrix Constituent Secretion
Complement Activation
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Gene Expression
Positive Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Angiogenesis
Activation Of Protein Kinase Activity
Positive Regulation Of Collagen Biosynthetic Process
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Mitotic Nuclear Division
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Stress Fiber Assembly
Positive Regulation Of Cell Cycle Arrest
Cellular Response To Hypoxia
Mitotic Cell Cycle Arrest
Fibroblast Activation
Negative Regulation Of Fibroblast Growth Factor Production
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Extracellular Matrix Assembly
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin
Positive Regulation Of Endothelial Cell Apoptotic Process
Positive Regulation Of DNA Biosynthetic Process
Pathways
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS
Heel bone mineral density (
30598549
)
Multiple sclerosis (
31604244
)
Pre-treatment viral load in HIV-1 infection (
31219150
)
Interacting Genes
3 interacting genes:
AKT1
CDK1
PLK1
Entrez ID
28984
HPRD ID
17970
Ensembl ID
ENSG00000102760
Uniprot IDs
Q9H4X1
PDB IDs
Enriched GO Terms of Interacting Partners
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