HECTD4

Description		HECT domain E3 ubiquitin protein ligase 4
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Glucose Metabolic Process Protein Ubiquitination Glucose Homeostasis
Pathways
Drugs
Diseases
GWAS		Alcohol consumption (max-drinks) ( 29460428) Alcohol dependence symptom count ( 29460428) Body mass index ( 26426971 28892062) Celiac disease and Rheumatoid arthritis ( 26546613) Coffee consumption ( 29367735) Diastolic blood pressure ( 27736895) Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Granulocyte count ( 27863252) HDL cholesterol levels ( 28334899 31087446) Hematological and biochemical traits ( 31902109) High density lipoprotein cholesterol levels ( 30718733) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Mean corpuscular hemoglobin concentration ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolic syndrome ( 30382898) Myeloid white cell count ( 27863252) Myocardial infarction ( 30226566) Neutrophil count ( 27863252) Reaction time ( 29844566) Red cell distribution width ( 32888494) Response to alcohol consumption (flushing response) ( 29460428) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Serum uric acid levels ( 29124443 32514006) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Thoracic-to-hip circumference ratio ( 26675016) Type 2 diabetes ( 32499647) Urate levels ( 31578528) White blood cell count ( 27863252)
Interacting Genes		2 interacting genes: UBE2D2 UBE2L3
Entrez ID		283450
HPRD ID		08170
Ensembl ID		ENSG00000173064
Uniprot IDs		F8VWT9
PDB IDs
Enriched GO Terms of Interacting Partners?
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