SLCO1B3

Description		solute carrier organic anion transporter family member 1B3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane
	Molecular Function	Organic Anion Transmembrane Transporter Activity Bile Acid Transmembrane Transporter Activity Sodium-independent Organic Anion Transmembrane Transporter Activity
	Biological Process	Organic Anion Transport Bile Acid And Bile Salt Transport Sodium-independent Organic Anion Transport Transmembrane Transport
Pathways		Recycling of bile acids and salts Heme degradation Defective SLCO1B3 causes hyperbilirubinemia, Rotor type (HBLRR) Transport of organic anions
Drugs		Clarithromycin Gemfibrozil Ginsenoside Rb1 Ginsenoside Rg1
Diseases
GWAS		Bilirubin levels ( 31801373 19419973 31319653 23371916 20639394) Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 27400856) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Height ( 18391951) Parkinson's disease progression (cognitive) ( 33111402) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Total bilirubin levels ( 29403010)
Interacting Genes		1 interacting genes: CCKBR
Entrez ID		28234
HPRD ID		12021
Ensembl ID		ENSG00000111700
Uniprot IDs		B3KP78 Q9NPD5
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?