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INPP5J
Description
inositol polyphosphate-5-phosphatase J
Image
No pdb structure
GO Annotations
Cellular Component
Ruffle
Cytoplasm
Cytosol
Plasma Membrane
Extrinsic Component Of Membrane
Growth Cone
Dendritic Shaft
Molecular Function
Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity
Inositol-polyphosphate 5-phosphatase Activity
Protein Binding
SH3 Domain Binding
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity
Inositol-1,4,5-trisphosphate 5-phosphatase Activity
Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity
Biological Process
Phosphatidylinositol Biosynthetic Process
Negative Regulation Of Neuron Projection Development
Negative Regulation Of Microtubule Polymerization
Negative Regulation Of Peptidyl-serine Phosphorylation
Inositol Phosphate Metabolic Process
Inositol Phosphate Dephosphorylation
Phosphatidylinositol Dephosphorylation
Pathways
Synthesis of PIPs at the plasma membrane
Synthesis of IP2, IP, and Ins in the cytosol
Synthesis of IP3 and IP4 in the cytosol
Drugs
Diseases
GWAS
Fish- and plant-related diet (
32066663
)
Gut microbiota (beta diversity) (
27723756
)
Oily fish consumption (
32066663
)
Pork consumption (
32066663
)
Interacting Genes
18 interacting genes:
CDC23
CEP70
DNAJA3
EFHC2
EPS8
FXR2
GOLGA2
HSF2BP
MEOX1
MEOX2
PELI1
PICK1
PRKAR1B
PSME3
RINT1
TLE5
TRIM27
TRIM54
Entrez ID
27124
HPRD ID
07573
Ensembl ID
ENSG00000185133
Uniprot IDs
A0A087WVS7
B4DF95
Q15735
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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