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PLA2G2D
Description
phospholipase A2 group IID
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Molecular Function
Phospholipase A2 Activity
Calcium Ion Binding
Phospholipid Binding
Heparin Binding
Heparan Sulfate Proteoglycan Binding
Calcium-dependent Phospholipase A2 Activity
Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine)
Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)
Biological Process
CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Differentiation
Regulation Of Acute Inflammatory Response To Antigenic Stimulus
Phospholipid Metabolic Process
Phosphatidic Acid Biosynthetic Process
Inflammatory Response
Lipid Catabolic Process
Phosphatidylglycerol Acyl-chain Remodeling
Phosphatidylinositol Acyl-chain Remodeling
Phosphatidylserine Acyl-chain Remodeling
Phosphatidylcholine Acyl-chain Remodeling
Phosphatidylethanolamine Acyl-chain Remodeling
Negative Regulation Of T Cell Proliferation
Phosphatidylethanolamine Metabolic Process
Phosphatidylcholine Metabolic Process
Arachidonic Acid Secretion
Pathways
Acyl chain remodelling of PC
Acyl chain remodelling of PS
Acyl chain remodelling of PE
Acyl chain remodelling of PI
Acyl chain remodelling of PG
Synthesis of PA
Drugs
Lauric acid
Stearic acid
Diseases
GWAS
Crohn's disease (
32581322
)
group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP (
31070471
)
Obesity-related traits (
23251661
)
Interacting Genes
1 interacting genes:
ADRB2
Entrez ID
26279
HPRD ID
07546
Ensembl ID
ENSG00000117215
Uniprot IDs
Q9UNK4
PDB IDs
Enriched GO Terms of Interacting Partners
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