MMACHC

Description		metabolism of cobalamin associated C
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GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Protein Binding Oxidoreductase Activity Transferase Activity Cobalamin Binding Demethylase Activity Cyanocobalamin Reductase (cyanide-eliminating) Activity Protein Homodimerization Activity Glutathione Binding FAD Binding
	Biological Process	Glutathione Metabolic Process Cobalamin Metabolic Process Demethylation
Pathways		Cobalamin (Cbl, vitamin B12) transport and metabolism Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
Drugs		Cyanocobalamin Hydroxocobalamin
Diseases		Methylmalonic aciduria (MMA)
GWAS		Blood protein levels ( 28240269) Homocysteine levels ( 23824729)
Novel Interacting Genes		1 novel interacting genes: KDM4A
Interacting Genes		1 interacting genes: MMADHC
Entrez ID		25974
HPRD ID		18585
Ensembl ID		ENSG00000132763
Uniprot IDs		A0A0C4DGU2 Q9Y4U1
PDB IDs		3SBY 3SBZ 3SC0 3SOM 5UOS
Enriched GO Terms of Interacting Partners?
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