GABRG3

Description		gamma-aminobutyric acid type A receptor subunit gamma3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Dendrite Membrane Chloride Channel Complex Neuron Projection Synapse Postsynaptic Membrane Postsynapse GABA-ergic Synapse Integral Component Of Synaptic Membrane GABA-A Receptor Complex
	Molecular Function	GABA-A Receptor Activity Inhibitory Extracellular Ligand-gated Ion Channel Activity Chloride Channel Activity Benzodiazepine Receptor Activity GABA-gated Chloride Ion Channel Activity Neurotransmitter Receptor Activity Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Signal Transduction Gamma-aminobutyric Acid Signaling Pathway Chemical Synaptic Transmission Ion Transmembrane Transport Regulation Of Membrane Potential Response To Drug Nervous System Process Synaptic Transmission, GABAergic Regulation Of Postsynaptic Membrane Potential Chloride Transmembrane Transport
Pathways		Signaling by ERBB4 GABA receptor activation GABA receptor activation
Drugs		Lorazepam Lorazepam Ethchlorvynol Enflurane Temazepam Temazepam Butabarbital Butalbital Phenytoin Etomidate Talbutal Pentobarbital Olanzapine Clobazam Clobazam Meprobamate Eszopiclone Alprazolam Alprazolam Metharbital Chlordiazepoxide Chlordiazepoxide Amoxapine Adinazolam Adinazolam Lamotrigine Lamotrigine Medroxyprogesterone acetate Clorazepic acid Clorazepic acid Acamprosate Midazolam Midazolam Flurazepam Flurazepam Isoflurane Primidone Halazepam Halazepam Propofol Diazepam Diazepam Oxazepam Oxazepam Triazolam Triazolam Ethanol Methoxyflurane Memantine Clonazepam Clonazepam Methyprylon Halothane Desflurane Flumazenil Estazolam Estazolam Sevoflurane Glutethimide Camazepam Camazepam Delorazepam Delorazepam Flunitrazepam Flunitrazepam Ethyl loflazepate Ethyl loflazepate Cloxazolam Cloxazolam Bromazepam Bromazepam Clotiazepam Clotiazepam Fludiazepam Ketazolam Ketazolam Prazepam Prazepam Quazepam Quazepam Cinolazepam Cinolazepam Nitrazepam Nitrazepam Prasterone Taurine Adipiplon Brotizolam Brotizolam Stiripentol Etizolam Etizolam Thiocolchicoside Brexanolone Apalutamide Remimazolam Remimazolam Benzodiazepine Benzodiazepine Pinazepam Pinazepam Medazepam Medazepam Loprazolam Loprazolam Doxefazepam Doxefazepam Lormetazepam Lormetazepam 5,7,2â€²-trihydroxy-6,8-dimethoxyflavone Nordazepam Nordazepam Oxazepam acetate Oxazepam acetate Cinazepam Cinazepam Bentazepam Bentazepam Mexazolam Mexazolam
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Anthropometric traits (multi-trait analysis) ( 30166351) Bitter beverage consumption ( 31046077) Corneal curvature ( 22969067) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) Gene methylation in lung tissue ( 25713168) General risk tolerance (MTAG) ( 30643258) High-grade serous ovarian cancer ( 31469419) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Skin pigmentation (conditioned on rs1426654 and rs35397) ( 31315583) Type 2 diabetes ( 30130595) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737) Weight ( 28552196)
Interacting Genes		1 interacting genes: GABARAP
Entrez ID		2567
HPRD ID		02579
Ensembl ID		ENSG00000182256
Uniprot IDs		Q99928
PDB IDs
Enriched GO Terms of Interacting Partners?
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