AMACR

Description		alpha-methylacyl-CoA racemase
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Peroxisome Peroxisomal Matrix Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Alpha-methylacyl-CoA Racemase Activity CoA-transferase Activity
	Biological Process	Protein Targeting To Peroxisome Bile Acid Biosynthetic Process Bile Acid Metabolic Process Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase
Pathways		Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Synthesis of bile acids and bile salts via 24-hydroxycholesterol Beta-oxidation of pristanoyl-CoA Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases		Peroxisomal beta-oxidation enzyme deficiency, including: Acyl-CoA oxidase (ACOX) deficiency; D-bifunctional protein (DBP) deficiency; Perrault syndrome; Sterol carrier protein X (SCPx) deficiency; 2-Methylacyl-CoA racemase (AMCR) deficiency; Hypercholanemia Congenital bile acid synthesis defect (CBAS), including: 3-beta-hydroxy-delta-5-C27-steroid oxidoreductase deficiency (CBAS1); Delta(4)-3-oxosteroid 5-beta-reductase deficiency (CBAS2); Oxysterol 7-alpha-hydroxylase deficiency (CBAS3); Alpha-methylacyl-CoA racemase deficiency (CBAS4)
GWAS		Estimated glomerular filtration rate ( 30604766)
Interacting Genes		1 interacting genes: PEX5
Entrez ID		23600
HPRD ID		05134
Ensembl ID		ENSG00000242110
Uniprot IDs		Q9UHK6
PDB IDs
Enriched GO Terms of Interacting Partners?
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