ASTN2

Description		astrotactin 2
Image
GO Annotations	Cellular Component	Endosome Early Endosome Late Endosome Cell Cortex Integral Component Of Membrane Clathrin-coated Vesicle Perikaryon Cell Pole
	Molecular Function	Calcium Ion Binding Inositol 1,3,4,5 Tetrakisphosphate Binding
	Biological Process	Neuron Migration Neuron Cell-cell Adhesion Protein Transport Establishment Of Body Hair Planar Orientation Negative Regulation Of Protein Localization To Cell Surface
Pathways
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) Attention deficit hyperactivity disorder ( 18839057) Bipolar disorder and schizophrenia ( 20889312) Body mass index ( 28892062 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Brain morphology (MOSTest) ( 32665545) Breast cancer ( 29059683) Caudal middle frontal gyrus volume ( 31530798) Chronic obstructive pulmonary disease ( 30804561) Dentate gyrus granule cell layer volume ( 30279459) Depression ( 29700475) Economic and political preferences (fairness) ( 22566634) Estimated glomerular filtration rate ( 31152163 31451708 30604766) Estimated glomerular filtration rate in non-diabetics ( 31451708) Feeling guilty ( 29500382) FEV1 ( 30804560) Glomerular filtration rate (creatinine) ( 28452372) Glucose homeostasis traits ( 25524916) Headache ( 29397368) Heel bone mineral density ( 30598549) Height ( 31562340) Hip shape (DXA scan) ( 30320955) Hippocampal subfield CA4 volume ( 30279459) Hippocampal volume ( 22504421) Idiopathic osteonecrosis of the femoral head ( 28000841) Immune response to anthrax vaccine ( 22658931) Lifetime average cigarettes per day in chronic obstructive pulmonary disease ( 21685187) Lung function (FEV1/FVC) ( 28166213 26635082 30804560) Medication use (antimigraine preparations) ( 31015401) Metabolite levels ( 23823483) Migraine ( 22683712 27182965 27322543) Migraine - clinic-based ( 23793025) Migraine without aura ( 23793025 27322543) Multisite chronic pain ( 31194737) Nonunion in individuals with fractures ( 30680360) Obesity-related traits ( 23251661) Osteoarthritis (hip) ( 30664745 30374069) Peak expiratory flow ( 30804560) PR interval ( 32439900) Pulmonary function (smoking interaction) ( 23284291) Response to antipsychotic treatment ( 20195266) Subiculum volume ( 30279459) Survival in pancreatic cancer ( 28470677) Total hippocampal volume ( 30279459) Transverse temporal cortex volume ( 31530798)
Novel Interacting Genes		3 novel interacting genes: POLE3 TNC TRIM32
Interacting Genes		1 interacting genes: CHRM5
Entrez ID		23245
HPRD ID		12498
Ensembl ID		ENSG00000148219
Uniprot IDs		B3KN99 B7ZKP4 B7ZKP5 O75129 X6R5P2
PDB IDs		5J67 5J68 5J69
Enriched GO Terms of Interacting Partners?
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