FLT3LG

Description		fms related receptor tyrosine kinase 3 ligand
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Cell Surface Membrane Integral Component Of Membrane
	Molecular Function	Signaling Receptor Binding Cytokine Activity Protein Binding Receptor Tyrosine Kinase Binding
	Biological Process	MAPK Cascade Signal Transduction Positive Regulation Of Cell Population Proliferation Cytokine-mediated Signaling Pathway Positive Regulation Of Natural Killer Cell Proliferation Embryonic Hemopoiesis
Pathways		PI3K Cascade PIP3 activates AKT signaling Constitutive Signaling by Aberrant PI3K in Cancer RAF/MAP kinase cascade PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling FLT3 Signaling FLT3 Signaling STAT5 Activation Negative regulation of FLT3 FLT3 signaling through SRC family kinases FLT3 signaling through SRC family kinases FLT3 signaling by CBL mutants
Drugs
Diseases
GWAS		Monocyte percentage of white cells ( 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269)
Interacting Genes		4 interacting genes: FLT3 KITLG KRTAP5-9 PFN2
Entrez ID		2323
HPRD ID		02477
Ensembl ID		ENSG00000090554
Uniprot IDs		B7ZLY4 M0QYM9 P49771
PDB IDs		1ETE 3QS7 3QS9
Enriched GO Terms of Interacting Partners?
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