CEP131

Description		centrosomal protein 131
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Manchette Centrosome Cytosol Microtubule Cytoskeleton Centriolar Satellite Ciliary Transition Zone Ciliary Basal Body Intracellular Membrane-bounded Organelle Intercellular Bridge Sperm Head-tail Coupling Apparatus
	Molecular Function	Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Multicellular Organism Development Sperm Axoneme Assembly Positive Regulation Of Cell Population Proliferation Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Centrosome Duplication Intraciliary Transport Involved In Cilium Assembly Cilium Assembly Protein Localization To Centrosome Positive Regulation Of Intracellular Protein Transport Ciliary Basal Body-plasma Membrane Docking Manchette Assembly Non-motile Cilium Assembly Intramanchette Transport
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Frontotemporal dementia ( 26154020) IgG N-glycosylation phenotypes (multivariate analysis) ( 32128391)
Interacting Genes		3 interacting genes: MAPKAPK2 YWHAE YWHAZ
Entrez ID		22994
HPRD ID		16532
Ensembl ID		ENSG00000141577
Uniprot IDs		I3L2J8 Q9UPN4
PDB IDs
Enriched GO Terms of Interacting Partners?
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